Abstract：The N450 refers to a more negative event-related potentials (ERPs) component in the incongruent condition than that in the congruent or neutral conditions in Stroop task duringthe 350-500 ms time window, which may reflects a keybiomarker of interference effect in cognitive control. It is of great methodological significance for insight into the nature of cognitive interference in conflict processing and for corresponding clinical studies. The present articlereviewed a variety of studies on the psychological implicationsof the N450 by different experimental tasks and variants involving perceptual conflict or response conflict, conflict monitoring or conflict resolution. The clinical application and individual difference concerning the N450 were additionally investigated. Future research was suggestedto elucidate the controversies on mental mechanism of the N450 by combining more valid experimental paradigms and technological approaches and to extend the corresponding applied research.
浙公网安备 33010602002302号 备案号：